Luciferase activity was quantified and normalized relative to a 4 hour stimulation with 1 mM soluble amidated compound P (s-SubP-NH2) on the corresponding NK receptor subtype. Information characterize the mean six SEM from three independent experiments
Recombinant SubP MTL mediated signaling predicts action of a corresponding SMAL on neurokinin receptors. Each tSubP and l-SubP-COOH activate NK1R (panels A and D) and NK3R (panels C and F)…