Raft preparation, D.T.L. and G.C.F.; writing–review and editing, E.P., T.G., V.S.M., M.C. and G.C.F.; visualization, D.T.L.; supervision, E.P., V.S.M., M.C. and G.C.F.; project administration, E.P. and G.C.F.; funding acquisition, E.P. and G.C.F. All authors have read and agreed for the published version from the manuscript. Funding: This research received no external funding. Institutional Review Board Statement: Not applicable. The protocols on the study had been approved by the academic board from the Veterinary Faculty on the University of Thessaly, meeting 34/03.04.19. Landiolol manufacturer Informed Consent Statement: Not applicable. Information Availability Statement: Most information presented in this study are inside the Supplementary Components. The remaining information are available on request from the corresponding author. The data are usually not publicly out there as they form component of the PhD thesis with the first author, which has not however been examined, authorized, and uploaded in the official depository of PhD theses from Greek Universities. Acknowledgments: The help received by the veterinarians, who chosen the flocks and arranged the visits for sample collection, is gratefully acknowledged. Conflicts of Interest: The authors declare no conflict of interest.Biology 2021, 10,13 ofAppendix ATable A1. Variables (n = 25) evaluated for possible association with presence of antibiotic resistance in staphylococci isolated in the bulk-tank milk of 325 sheep flocks in Greece. Management program applied inside the flock (description in accordance with EFSA classification) [47] Month into the lactation period at sampling (month) Machine- or hand-milking (description) No. of ewes within the flock (no.) Total milk quantity per ewe obtained through the preceding milking period (litres) Average number of lambs born per ewe (no.) Collaboration having a veterinarian (yes/no) Total visits produced annually by veterinarians towards the flock in the course of the preceding season (no.) Clinical mastitis annual incidence threat in the flock Age of lamb removal from their dams (days) Daily variety of milking sessions (no.) Duration in the dry-period (months) Implies of calculating reside bodyweight for the administration of pharmaceutical items (weighing/estimation) Routine overdosing (in comparison with dose prescribed) of pharmaceuticals (yes/no) Annual frequency of systemic disinfections inside the farm (no. of occasions) Routine administration of antimicrobials in newborns (yes/no) Vaccination against mastitis (yes/no) Administration of `dry-ewe’ treatment at the finish in the lactation period (yes/no) Use of teat disinfection following milking (yes/no) Age with the farmer (years) Length of previous animal farming experience on the farmer (years) Education from the farmer (description) Farmer by profession (yes/no) Loved ones tradition in farming (yes/no) Presence of operating staff inside the flock (yes/no)
biologyCommunicationDisappearance of Temporal Collinearity in Vertebrates and Its Eventual ReappearanceSpyros PapageorgiouInstitute of Biosciences and Applications, NCSR `Demokritos’, 15310 Athens, Greece; [email protected] Summary: In 1999 T. Kondo and D. Duboule performed excisions of posterior upstream DNA domains in mouse embryos and they observed that for an extended excision (such as Evx gene) the Hox genes on the cluster had been simultaneously expressed together with the initially Hoxd1 gene `as if’ Temporal Collinearity (TC) had disappeared. Based on a Biophysical Model (BM) for the duration of Hox gene expression, Hox clusters behave similar toexpanding elastic sprin.