Om H460- and CSC-derived tumors growing in SCID mice (five tumors per group) and concentrations of different tumor-producing cytokines, Activin A Receptor Type 2B (ACVR2B) Proteins manufacturer chemokines, angiogenic and development components were analyzed applying multiplex kits. Only elements with significant differences in their concentrations (at the very least p,0.05) are included. doi:10.1371/journal.pone.0003077.tPLoS One www.plosone.orgLung CSCs and Cytokine Networkembryonic antigens. To test this hypothesis, an evaluation of serologically detectable cancer antigens (AFP, CEA, CA-125, CA 19-9, CA 15-3, and CA72-4) within the CSC- and H460-derived tumors was performed. Carcinoembryonic antigen (CEA) was by far the most prevalent cancer antigen within the tested tumor lysates irrespective of origin; on the other hand, CSC-derived tumors contained three-fold greater CEA concentrations than