Product Name :
Fluorescein-thiourea-PEG2-azide
Description:
Fluorescein-thiourea-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
1146195-72-3
Molecular Weight:
563.58
Formula:
C27H25N5O7S
Chemical Name:
3-{2-[2-(2-azidoethoxy)ethoxy]ethyl}-1-{3′,6′-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9′-xanthen]-5-yl}thiourea
Smiles :
[N-]=[N+]=NCCOCCOCCNC(=S)NC1=CC2C(=O)OC3(C4=CC=C(O)C=C4OC4=CC(O)=CC=C34)C=2C=C1
InChiKey:
ZLPFCAHUXVVHPW-UHFFFAOYSA-N
InChi :
InChI=1S/C27H25N5O7S/c28-32-30-8-10-37-12-11-36-9-7-29-26(40)31-16-1-4-20-19(13-16)25(35)39-27(20)21-5-2-17(33)14-23(21)38-24-15-18(34)3-6-22(24)27/h1-6,13-15,33-34H,7-12H2,(H2,29,31,40)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Fluorescein-thiourea-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1146195-72-3|Molecular Weight: 563.58|Formula: C27H25N5O7S|Chemical Name: 3-{2-[2-(2-azidoethoxy)ethoxy]ethyl}-1-{3′,6′-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9′-xanthen]-5-yl}thiourea|Smiles: [N-]=[N+]=NCCOCCOCCNC(=S)NC1=CC2C(=O)OC3(C4=CC=C(O)C=C4OC4=CC(O)=CC=C34)C=2C=C1|InChiKey: ZLPFCAHUXVVHPW-UHFFFAOYSA-N|InChi: InChI=1S/C27H25N5O7S/c28-32-30-8-10-37-12-11-36-9-7-29-26(40)31-16-1-4-20-19(13-16)25(35)39-27(20)21-5-2-17(33)14-23(21)38-24-15-18(34)3-6-22(24)27/h1-6,13-15,33-34H,7-12H2,(H2,29,31,40)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Deferiprone} medchemexpress|{Deferiprone} Anti-infection|{Deferiprone} Purity & Documentation|{Deferiprone} In Vivo|{Deferiprone} custom synthesis|{Deferiprone} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Pritelivir} MedChemExpress|{Pritelivir} HSV|{Pritelivir} Purity & Documentation|{Pritelivir} Purity|{Pritelivir} custom synthesis|{Pritelivir} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23577779 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|