Product Name :
NVS-PI3-4
Description:
NVS-PI3-4 is a specific PI3Kγ inhibitor. NVS-PI3-4 can be used for the research of allergies, inflammatory and cancer diseases.
CAS:
941580-60-5
Molecular Weight:
402.51
Formula:
C20H26N4O3S
Chemical Name:
3-({[5-(4-acetylphenyl)-4-methyl-1,3-thiazol-2-yl]carbamoyl}amino)-N-tert-butylpropanamide
Smiles :
CC(=O)C1=CC=C(C=C1)C1SC(NC(=O)NCCC(=O)NC(C)(C)C)=NC=1C
InChiKey:
IUPXLLWDLOWEBR-UHFFFAOYSA-N
InChi :
InChI=1S/C20H26N4O3S/c1-12-17(15-8-6-14(7-9-15)13(2)25)28-19(22-12)23-18(27)21-11-10-16(26)24-20(3,4)5/h6-9H,10-11H2,1-5H3,(H,24,26)(H2,21,22,23,27)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
NVS-PI3-4 is a specific PI3Kγ inhibitor. NVS-PI3-4 can be used for the research of allergies, inflammatory and cancer diseases.|Product information|CAS Number: 941580-60-5|Molecular Weight: 402.51|Formula: C20H26N4O3S|Chemical Name: 3-({[5-(4-acetylphenyl)-4-methyl-1,3-thiazol-2-yl]carbamoyl}amino)-N-tert-butylpropanamide|Smiles: CC(=O)C1=CC=C(C=C1)C1SC(NC(=O)NCCC(=O)NC(C)(C)C)=NC=1C|InChiKey: IUPXLLWDLOWEBR-UHFFFAOYSA-N|InChi: InChI=1S/C20H26N4O3S/c1-12-17(15-8-6-14(7-9-15)13(2)25)28-19(22-12)23-18(27)21-11-10-16(26)24-20(3,4)5/h6-9H,10-11H2,1-5H3,(H,24,26)(H2,21,22,23,27)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (621.{{Rociletinib} site|{Rociletinib} Protein Tyrosine Kinase/RTK|{Rociletinib} Purity & Documentation|{Rociletinib} In Vivo|{Rociletinib} manufacturer|{Rociletinib} Epigenetic Reader Domain} 10 mM; Need ultrasonic).{{Relacorilant} site|{Relacorilant} Vitamin D Related/Nuclear Receptor|{Relacorilant} Biological Activity|{Relacorilant} In stock|{Relacorilant} supplier|{Relacorilant} Autophagy} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32180353 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|NVS-PI3-4 shows an exquisite cellular selectivity for PI3Kγ. NVS-PI3-4 reduces IgE/antigen-mediated phosphorylation of PKB/Akt in p110δDA. NVS-PI3-4 (5 μM; 30 minutes; BMMCs) is not accumulate in specifically in mast cells.|Products are for research use only. Not for human use.|