Product Name :
N-Methyl-N’-methyl-O-(m-PEG4)-O’-(azide-PEG4)-Cy3
Description:
N-Methyl-N’-methyl-O-(m-PEG4)-O’-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2107273-64-1
Molecular Weight:
860.48
Formula:
C44H66ClN5O10
Chemical Name:
2-[(1E)-3-[(2E)-5-[(14-azido-3,6,9,12-tetraoxatetradecan-1-yl)oxy]-1,3,3-trimethyl-2,3-dihydro-1H-indol-2-ylidene]prop-1-en-1-yl]-1,3,3-trimethyl-5-(2,5,8,11-tetraoxatridecan-13-yloxy)-3H-indol-1-ium chloride
Smiles :
[Cl-].COCCOCCOCCOCCOC1=CC2=C(C=C1)[N+](C)=C(/C=C/C=C1/N(C)C3=CC=C(C=C3C/1(C)C)OCCOCCOCCOCCOCCN=[N+]=[N-])C2(C)C
InChiKey:
FHRNKBLFTPHSBL-UHFFFAOYSA-M
InChi :
InChI=1S/C44H66N5O10.ClH/c1-43(2)37-33-35(58-31-29-56-27-25-54-22-21-52-18-17-50-7)11-13-39(37)48(5)41(43)9-8-10-42-44(3,4)38-34-36(12-14-40(38)49(42)6)59-32-30-57-28-26-55-24-23-53-20-19-51-16-15-46-47-45;/h8-14,33-34H,15-32H2,1-7H3;1H/q+1;/p-1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
N-Methyl-N’-methyl-O-(m-PEG4)-O’-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.{{Laropiprant} web|{Laropiprant} GPCR/G Protein|{Laropiprant} NF-κB|{Laropiprant} Biological Activity|{Laropiprant} In Vivo|{Laropiprant} supplier} |Product information|CAS Number: 2107273-64-1|Molecular Weight: 860.{{Lorundrostat} medchemexpress|{Lorundrostat} Vitamin D Related/Nuclear Receptor|{Lorundrostat} Technical Information|{Lorundrostat} Formula|{Lorundrostat} manufacturer|{Lorundrostat} Autophagy} 48|Formula: C44H66ClN5O10|Chemical Name: 2-[(1E)-3-[(2E)-5-[(14-azido-3,6,9,12-tetraoxatetradecan-1-yl)oxy]-1,3,3-trimethyl-2,3-dihydro-1H-indol-2-ylidene]prop-1-en-1-yl]-1,3,3-trimethyl-5-(2,5,8,11-tetraoxatridecan-13-yloxy)-3H-indol-1-ium chloride|Smiles: [Cl-].PMID:32896944 COCCOCCOCCOCCOC1=CC2=C(C=C1)[N+](C)=C(/C=C/C=C1/N(C)C3=CC=C(C=C3C/1(C)C)OCCOCCOCCOCCOCCN=[N+]=[N-])C2(C)C|InChiKey: FHRNKBLFTPHSBL-UHFFFAOYSA-M|InChi: InChI=1S/C44H66N5O10.ClH/c1-43(2)37-33-35(58-31-29-56-27-25-54-22-21-52-18-17-50-7)11-13-39(37)48(5)41(43)9-8-10-42-44(3,4)38-34-36(12-14-40(38)49(42)6)59-32-30-57-28-26-55-24-23-53-20-19-51-16-15-46-47-45;/h8-14,33-34H,15-32H2,1-7H3;1H/q+1;/p-1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|