Product Name :
L-689502
Description:
L-689502 is a potent inhibitor of HIV-l protease with an IC50 of 1 nM.
CAS:
138483-63-3
Molecular Weight:
673.84
Formula:
C39H51N3O7
Chemical Name:
tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl-5-(4-[2-(morpholin-4-yl)ethoxy]phenylmethyl)-1-phenylpentan-2-yl]carbamate
Smiles :
CC(C)(C)OC(=O)N[C@@H](CC1C=CC=CC=1)[C@@H](O)C[C@@H](CC1C=CC(=CC=1)OCCN1CCOCC1)C(=O)N[C@@H]1[C@H](O)CC2C=CC=CC=21
InChiKey:
IYLCQJSWFWQHCD-AIIVFDHXSA-N
InChi :
InChI=1S/C39H51N3O7/c1-39(2,3)49-38(46)40-33(24-27-9-5-4-6-10-27)34(43)26-30(37(45)41-36-32-12-8-7-11-29(32)25-35(36)44)23-28-13-15-31(16-14-28)48-22-19-42-17-20-47-21-18-42/h4-16,30,33-36,43-44H,17-26H2,1-3H3,(H,40,46)(H,41,45)/t30-,33+,34+,35-,36+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.Anti-Mouse IL-1a Antibody supplier
Additional information:
L-689502 is a potent inhibitor of HIV-l protease with an IC50 of 1 nM.Alisertib custom synthesis |Product information|CAS Number: 138483-63-3|Molecular Weight: 673.84|Formula: C39H51N3O7|Chemical Name: tert-butyl N-[(2S,3S,5R)-3-hydroxy-5-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl-5-(4-[2-(morpholin-4-yl)ethoxy]phenylmethyl)-1-phenylpentan-2-yl]carbamate|Smiles: CC(C)(C)OC(=O)N[C@@H](CC1C=CC=CC=1)[C@@H](O)C[C@@H](CC1C=CC(=CC=1)OCCN1CCOCC1)C(=O)N[C@@H]1[C@H](O)CC2C=CC=CC=21|InChiKey: IYLCQJSWFWQHCD-AIIVFDHXSA-N|InChi: InChI=1S/C39H51N3O7/c1-39(2,3)49-38(46)40-33(24-27-9-5-4-6-10-27)34(43)26-30(37(45)41-36-32-12-8-7-11-29(32)25-35(36)44)23-28-13-15-31(16-14-28)48-22-19-42-17-20-47-21-18-42/h4-16,30,33-36,43-44H,17-26H2,1-3H3,(H,40,46)(H,41,45)/t30-,33+,34+,35-,36+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32809502 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Both L694746 and L-689502 inhibit HIV-l ptotease activity in a concentration-dependent manner. Pepstatin is much less potent than either compound exhibiting an IC50 of 2 μM. L694746 is as potent as L-689502 in inhibiting the HIV-l protease despite being structurally different from L-689502.|Products are for research use only. Not for human use.|