Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This article is distributed below the terms of the Creative Commons Attribution-NonCommercial three.0 License (http://www.creativecommons.org/MG-132 biological activity licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution with the perform without further permission supplied the original function is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).two water content material, volume, or frequency of stools.11 A decrease in consistency (ie, soft or liquid) and a rise inside the frequency of bowel movements to three stools per day have frequently been employed as a definition for epidemiological investigations. Based on a community-based study point of view, diarrhea is defined as no less than three or far more loose stools within a 24-hour period.12 A diarrheal episode is regarded as because the passage of 3 or much more loose or liquid stools in 24 hours before presentation for care, that is considered essentially the most practicable in young children and adults.13 Having said that, prolonged and persistent diarrhea can last among 7 and 13 days and no less than 14 days, respectively.14,15 The disease is very sensitive to climate, showing seasonal variations in a lot of sites.16 The climate sensitivity of diarrheal illness is consistent with observations in the direct effects of climate variables on the causative GSK343MedChemExpress GSK343 agents. Temperature and relative humidity possess a direct influence on the price of replication of bacterial and protozoan pathogens and on the survival of enteroviruses within the atmosphere.17 Wellness care journal.pone.0169185 in search of is recognized to be a result of a complicated behavioral approach that may be influenced by a number of elements, like socioeconomic and demographic and qualities, perceived want, accessibility, and service availability.Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This short article is distributed beneath the terms with the Inventive Commons Attribution-NonCommercial three.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution of your function without the need of further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).two water content material, volume, or frequency of stools.11 A decrease in consistency (ie, soft or liquid) and an increase within the frequency of bowel movements to three stools each day have often been employed as a definition for epidemiological investigations. Determined by a community-based study perspective, diarrhea is defined as at the very least three or a lot more loose stools within a 24-hour period.12 A diarrheal episode is thought of because the passage of three or more loose or liquid stools in 24 hours before presentation for care, that is viewed as probably the most practicable in young children and adults.13 Even so, prolonged and persistent diarrhea can final involving 7 and 13 days and at least 14 days, respectively.14,15 The illness is extremely sensitive to climate, displaying seasonal variations in several sites.16 The climate sensitivity of diarrheal disease is constant with observations from the direct effects of climate variables on the causative agents. Temperature and relative humidity possess a direct influence on the rate of replication of bacterial and protozoan pathogens and on the survival of enteroviruses in the atmosphere.17 Wellness care journal.pone.0169185 seeking is recognized to be a outcome of a complicated behavioral approach that may be influenced by various components, such as socioeconomic and demographic and characteristics, perceived have to have, accessibility, and service availability.