Product Name :
AP-1/NF-κB activation inhibitor 1
Description:
AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor (IC50=1 μM), without blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells.
CAS:
188936-12-1
Molecular Weight:
344.25
Formula:
C13H11F3N4O4
Chemical Name:
ethyl 4-[(3-methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)amino]-2-(trifluoromethyl)pyrimidine-5-carboxylate
Smiles :
CC1=CC(=O)N(NC2=NC(=NC=C2C(=O)OCC)C(F)(F)F)C1=O
InChiKey:
JWIIKHRJOUQCQG-UHFFFAOYSA-N
InChi :
InChI=1S/C13H11F3N4O4/c1-3-24-11(23)7-5-17-12(13(14,15)16)18-9(7)19-20-8(21)4-6(2)10(20)22/h4-5H,3H2,1-2H3,(H,17,18,19)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Irbesartan} MedChemExpress|{Irbesartan} GPCR/G Protein|{Irbesartan} Protocol|{Irbesartan} Purity|{Irbesartan} custom synthesis|{Irbesartan} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor (IC50=1 μM), without blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells.{{MSAB} medchemexpress|{MSAB} β-catenin|{MSAB} Purity & Documentation|{MSAB} Data Sheet|{MSAB} supplier|{MSAB} Cancer} |Product information|CAS Number: 188936-12-1|Molecular Weight: 344.PMID:28440459 25|Formula: C13H11F3N4O4|Chemical Name: ethyl 4-[(3-methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)amino]-2-(trifluoromethyl)pyrimidine-5-carboxylate|Smiles: CC1=CC(=O)N(NC2=NC(=NC=C2C(=O)OCC)C(F)(F)F)C1=O|InChiKey: JWIIKHRJOUQCQG-UHFFFAOYSA-N|InChi: InChI=1S/C13H11F3N4O4/c1-3-24-11(23)7-5-17-12(13(14,15)16)18-9(7)19-20-8(21)4-6(2)10(20)22/h4-5H,3H2,1-2H3,(H,17,18,19)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (726.22 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|