Product Name :
Apovincaminic acid hydrochloride salt
Description:
Apovincaminic acid hydrochloride salt is an orally active and brain-penetrant main active metabolite of Vinpocetine (VP). Apovincaminic acid hydrochloride salt exerts a neuroprotective type of action.
CAS:
72296-47-0
Molecular Weight:
358.86
Formula:
C20H23ClN2O2
Chemical Name:
(15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.0²,⁷.0⁸,¹⁸.0¹⁵,¹⁹]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylic acid hydrochloride
Smiles :
Cl.CC[C@@]12CCCN3CCC4=C([C@H]13)N(C(=C2)C(O)=O)C1=CC=CC=C41
InChiKey:
LXMYBTYOASVVKL-VDWUQFQWSA-N
InChi :
InChI=1S/C20H22N2O2.ClH/c1-2-20-9-5-10-21-11-8-14-13-6-3-4-7-15(13)22(17(14)18(20)21)16(12-20)19(23)24;/h3-4,6-7,12,18H,2,5,8-11H2,1H3,(H,23,24);1H/t18-,20+;/m1./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tranylcypromine} MedChemExpress|{Tranylcypromine} Neuronal Signaling|{Tranylcypromine} Biological Activity|{Tranylcypromine} Data Sheet|{Tranylcypromine} supplier|{Tranylcypromine} Epigenetics}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Apovincaminic acid hydrochloride salt is an orally active and brain-penetrant main active metabolite of Vinpocetine (VP). Apovincaminic acid hydrochloride salt exerts a neuroprotective type of action.|Product information|CAS Number: 72296-47-0|Molecular Weight: 358.{{Rhodamine B} medchemexpress|{Rhodamine B} {Fluorescent Dye}|{Rhodamine B} Protocol|{Rhodamine B} References|{Rhodamine B} custom synthesis|{Rhodamine B} Autophagy} 86|Formula: C20H23ClN2O2|Chemical Name: (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.PMID:24282960 6.2.0²,⁷.0⁸,¹⁸.0¹⁵,¹⁹]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylic acid hydrochloride|Smiles: Cl.CC[C@@]12CCCN3CCC4=C([C@H]13)N(C(=C2)C(O)=O)C1=CC=CC=C41|InChiKey: LXMYBTYOASVVKL-VDWUQFQWSA-N|InChi: InChI=1S/C20H22N2O2.ClH/c1-2-20-9-5-10-21-11-8-14-13-6-3-4-7-15(13)22(17(14)18(20)21)16(12-20)19(23)24;/h3-4,6-7,12,18H,2,5,8-11H2,1H3,(H,23,24);1H/t18-,20+;/m1./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Apovincaminic acid (10 mg/kg; i.p. twice daily for 4 days) effectively attenuates the behavioral deficits, and significantly decreases lesion size and the region of microglia activation. Apovincaminic acid (10 mg/kg; p.o.) is absorbed 50% of the dose comparing with i.v. administration in rats.|Products are for research use only. Not for human use.|