Product Name :
LY2940680
Description:
LY2940680, is a potent Hedgehog inhibitor with potential anticancer activity. LY2940680 inhibits cancer growth in cell lines containing a mutation in the gene encoding Smoothened that researchers had previously observed in patient with cancer who developed resistance to vismodegib.
CAS:
1258861-20-9
Molecular Weight:
512.50
Formula:
C26H24F4N6O
Chemical Name:
4-fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide
Smiles :
CN(C1CCN(CC1)C1=NN=C(C2=CC=NN2C)C2=CC=CC=C21)C(=O)C1=CC=C(F)C=C1C(F)(F)F
InChiKey:
SZBGQDXLNMELTB-UHFFFAOYSA-N
InChi :
InChI=1S/C26H24F4N6O/c1-34(25(37)20-8-7-16(27)15-21(20)26(28,29)30)17-10-13-36(14-11-17)24-19-6-4-3-5-18(19)23(32-33-24)22-9-12-31-35(22)2/h3-9,12,15,17H,10-11,13-14H2,1-2H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tebotelimab} web|{Tebotelimab} Immunology/Inflammation|{Tebotelimab} Protocol|{Tebotelimab} Purity|{Tebotelimab} custom synthesis|{Tebotelimab} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Zibotentan} medchemexpress|{Zibotentan} Endothelin Receptor|{Zibotentan} Biological Activity|{Zibotentan} Formula|{Zibotentan} manufacturer|{Zibotentan} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24456950
Additional information:
LY2940680, is a potent Hedgehog inhibitor with potential anticancer activity. LY2940680 inhibits cancer growth in cell lines containing a mutation in the gene encoding Smoothened that researchers had previously observed in patient with cancer who developed resistance to vismodegib.|Product information|CAS Number: 1258861-20-9|Molecular Weight: 512.50|Formula: C26H24F4N6O|Synonym:|Taladegib|Related CAS Number:|1258861-21-0 (Taladegib hydrochloride)|Chemical Name: 4-fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide|Smiles: CN(C1CCN(CC1)C1=NN=C(C2=CC=NN2C)C2=CC=CC=C21)C(=O)C1=CC=C(F)C=C1C(F)(F)F|InChiKey: SZBGQDXLNMELTB-UHFFFAOYSA-N|InChi: InChI=1S/C26H24F4N6O/c1-34(25(37)20-8-7-16(27)15-21(20)26(28,29)30)17-10-13-36(14-11-17)24-19-6-4-3-5-18(19)23(32-33-24)22-9-12-31-35(22)2/h3-9,12,15,17H,10-11,13-14H2,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|