Product Name :
ZM323881 Hydrochloride
Description:
ZM323881 is a potent and selective inhibitor of VEGF-R2 tyrosine kinase in vitro (IC(50) 50 microM). ZM323881 inhibits VEGF-A-induced endothelial cell proliferation (IC(50) = 8 nM) and VEGF-R2 tyrosine phosphorylation in vitro.
CAS:
193000-39-4
Molecular Weight:
411.86
Formula:
C22H19ClFN3O2
Chemical Name:
5-{[7-(benzyloxy)quinazolin-4-yl]amino}-4-fluoro-2-methylphenol hydrochloride
Smiles :
Cl.CC1=CC(F)=C(C=C1O)NC1=NC=NC2=CC(=CC=C21)OCC1C=CC=CC=1
InChiKey:
AVRHWGLIYGJSOD-UHFFFAOYSA-N
InChi :
InChI=1S/C22H18FN3O2.ClH/c1-14-9-18(23)20(11-21(14)27)26-22-17-8-7-16(10-19(17)24-13-25-22)28-12-15-5-3-2-4-6-15;/h2-11,13,27H,12H2,1H3,(H,24,25,26);1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
ZM323881 is a potent and selective inhibitor of VEGF-R2 tyrosine kinase in vitro (IC(50) 50 microM). ZM323881 inhibits VEGF-A-induced endothelial cell proliferation (IC(50) = 8 nM) and VEGF-R2 tyrosine phosphorylation in vitro.|Product information|CAS Number: 193000-39-4|Molecular Weight: 411.86|Formula: C22H19ClFN3O2|Chemical Name: 5-{[7-(benzyloxy)quinazolin-4-yl]amino}-4-fluoro-2-methylphenol hydrochloride|Smiles: Cl.CC1=CC(F)=C(C=C1O)NC1=NC=NC2=CC(=CC=C21)OCC1C=CC=CC=1|InChiKey: AVRHWGLIYGJSOD-UHFFFAOYSA-N|InChi: InChI=1S/C22H18FN3O2.{{Penicillin-Streptomycin} site|{Penicillin-Streptomycin} Epigenetics|{Penicillin-Streptomycin} Purity & Documentation|{Penicillin-Streptomycin} References|{Penicillin-Streptomycin} supplier} ClH/c1-14-9-18(23)20(11-21(14)27)26-22-17-8-7-16(10-19(17)24-13-25-22)28-12-15-5-3-2-4-6-15;/h2-11,13,27H,12H2,1H3,(H,24,25,26);1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Evodiamine} MedChemExpress|{Evodiamine} Purity & Documentation|{Evodiamine} Description|{Evodiamine} supplier|{Evodiamine} Autophagy} |Shelf Life: ≥360 days if stored properly.PMID:34645436 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|