Product Name :
Penitrem A
Description:
Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals.
CAS:
12627-35-9
Molecular Weight:
634.20
Formula:
C37H44ClNO6
Chemical Name:
(1R,2S,5R,6R,8R,9S,10R,12S,15S,16S,25R,27R,28S)-21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-(prop-1-en-2-yl)-7,11,32-trioxa-18-azadecacyclo[25.4.2.0²,¹⁶.0⁵,¹⁵.0⁶,⁸.0⁶,¹².0¹⁷,³¹.0¹⁹,³⁰.0²²,²⁹.0²⁵,²⁸]tritriaconta-17(31),19,21,29-tetraene-5,9,28-triol
Smiles :
CC1(C)O[C@@H]2[C@H]3CC[C@]4(O)[C@]56O[C@@H]5[C@@H](O)[C@H](O[C@H]6CC[C@@]4(C)[C@@]3(C)C3NC4=CC(Cl)=C5CC(=C)[C@H]6C[C@@H]1[C@]6(O)C5=C4C=32)C(C)=C
InChiKey:
JDUWHZOLEDOQSR-OGOYAGGGSA-N
InChi :
InChI=1S/C37H44ClNO6/c1-15(2)28-27(40)31-37(45-31)23(43-28)9-10-33(6)34(7)18(8-11-35(33,37)41)29-25-24-21(39-30(25)34)14-20(38)17-12-16(3)19-13-22(32(4,5)44-29)36(19,42)26(17)24/h14,18-19,22-23,27-29,31,39-42H,1,3,8-13H2,2,4-7H3/t18-,19-,22+,23+,27+,28-,29-,31-,33+,34-,35-,36+,37-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals.Dihydromethysticin In stock |Product information|CAS Number: 12627-35-9|Molecular Weight: 634.Obefazimod Autophagy 20|Formula: C37H44ClNO6|Chemical Name: (1R,2S,5R,6R,8R,9S,10R,12S,15S,16S,25R,27R,28S)-21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-(prop-1-en-2-yl)-7,11,32-trioxa-18-azadecacyclo[25.PMID:32496945 4.2.0²,¹⁶.0⁵,¹⁵.0⁶,⁸.0⁶,¹².0¹⁷,³¹.0¹⁹,³⁰.0²²,²⁹.0²⁵,²⁸]tritriaconta-17(31),19,21,29-tetraene-5,9,28-triol|Smiles: CC1(C)O[C@@H]2[C@H]3CC[C@]4(O)[C@]56O[C@@H]5[C@@H](O)[C@H](O[C@H]6CC[C@@]4(C)[C@@]3(C)C3NC4=CC(Cl)=C5CC(=C)[C@H]6C[C@@H]1[C@]6(O)C5=C4C=32)C(C)=C|InChiKey: JDUWHZOLEDOQSR-OGOYAGGGSA-N|InChi: InChI=1S/C37H44ClNO6/c1-15(2)28-27(40)31-37(45-31)23(43-28)9-10-33(6)34(7)18(8-11-35(33,37)41)29-25-24-21(39-30(25)34)14-20(38)17-12-16(3)19-13-22(32(4,5)44-29)36(19,42)26(17)24/h14,18-19,22-23,27-29,31,39-42H,1,3,8-13H2,2,4-7H3/t18-,19-,22+,23+,27+,28-,29-,31-,33+,34-,35-,36+,37-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|